Cardiology Lighthouse-Project PACE with targeted therapy in animal models
Within the framework of a BCPM lighthouse project, Researchers under the lead of Prof. Dr. Katja Odening have developed a "suppress and replace" gene therapy that successfully corrected life-threatening cardiac arrhythmias in an animal model. By targeting the genetic cause of Short QT syndrome type 1, the treatment normalized the heart's electrical signals and reduced the risk of sudden cardiac death. This targeted approach, delivered via viral vectors directly to the heart, offers a potential alternative to invasive defibrillators or medication, as presented at the BCPM cardiology symposium on 8 September 2025.
To the Media Release of the University