Institute of Biochemistry and Molecular Medicine

Eingang zum Institut

Research at the Institute focuses on the structure, function, and pharmacology of membrane proteins such as transporters, ion channels, and membrane receptors. A strong emphasis is put on the roles of these membrane proteins in human diseases such as cancer, cardiac disorders, preeclampsia, and neuropsychiatric disorders.

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Profile

  • Basic and specialized teaching in biochemistry, molecular and pharmaceutical biology, and molecular medicine. Teaching activities in the faculties of Medicine, Natural Sciences, and Vetsuisse to under- and postgraduate students (GCB)
  • Eight research groups
  • Interdisciplinary research on structure, function, and pharmacology of membrane proteins (transporters, ion channels, and receptors), with a strong emphasis on the roles of these membrane proteins in human diseases such as cancer, neuropsychiatric and cardiac disorders, preeclampsia and pathogen infection
  • Unravel working mechanisms of selected membrane proteins, discover new therapeutic targets
  • Former Leading House of the NCCR TransCure - Excellence in Membrane Transport Research
  • Associated PIs: Prof. Dr. med. Martin Müller, Division of Gynecology and Obstetrics, Lindenhofgruppe, Bern, Switzerland, and Prof. Dr. Andrea Chicca, Synendos Therapeutics AG, Basel, Switzerland

External Partners

D-BSSE & D-CHAB, ETH Zürich, Swiss Institute of Bioinformatics, University of Geneva, School of Medicine, University of Zurich, Hebrew University, Jerusalem, Israel, Hoffmann-La Roche, Pharma Research & Early Development, Basel, Switzerland, University of Nottingham, Department of Pharmacology, University of Cambridge, MRC LMB Cambridge, UK, Max-Planck-Institute, Munich, Technical University of Munich, Freising, Germany, Max-Planck-Institute, Marburg, Germany, Institute for Research in Biomedicine (IRB Barcelona), University of Barcelona, Spain, Laboratory of Molecular Electron Microscopy, The Rockefeller University, New York, NIH, NIAAA, Rockville, USA, Peter Mac Institute, Melbourne, Australia

Grants

  • SNSF project grants No. 310030_200380; 310030_201158;; 310030_184980; 310030_189220, 310030_197408; 310030_215274; 310030_ 10001444
  • SNSF Sinergia grants No. CRSII5_183481, CRSII-222818_10000189
  • Eccellenza Professorship (PCEFP3_ 194606)
  • UniBE Venture Fellowship
  • Wilhelm-Doerenkamp-Stiftung; Helmut Horten Stiftung; Novartis Research Foundation; Hans Sigrist Fondation (Three-Year-Fellowship); Marie Skłodowska-Curie Actions (nAChRs-CRC-PCa-IF-RI); BBSRC (UK) research grant BB/W014831/1, HSPO Human Frontier Science Program Organization